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Revision as of 16:20, 3 May 2011

The Bangham Lab

The Bangham Lab is part of the UEA D’Arcy Thompson Centre for computational biology.

Computational Biology

<sgallery width="160" height="280" showarrows="false" showcarousel="false" showinfopane="false" timed="true" delay="2000"> LabelledCropped_GPT_Snapdragon_2010-000250-0001.png LabelledCropped_GPT_Snapdragon_2010-000340-0001.png LabelledCropped_GPT_Snapdragon_2010-000490-0001.png LabelledCropped_GPT_Snapdragon_2010-000570-0002.png LabelledCropped_GPT_Snapdragon_2010-000570-0003.png LabelledCropped_GPT_Snapdragon_2010-000570-0004.png LabelledCropped_GPT_Snapdragon_2010-000570-0005.png LabelledCropped_GPT_Snapdragon_2010-000570-0007.png LabelledCropped_GPT_Snapdragon_2010-000570-0006.png LabelledCropped_GPT_Snapdragon_2010-000570-0001.png </sgallery>

More details

Genes and growing shapes

The aim is to understand how patterns of gene activity in biological organs influence the developing shape. A key notion is that genes may regulate direction independently of growth rate. We formalised our ideas in the Growing Polarised Tissue Framework (ref). To make it easy to develop ideas on the relationship between growth and form we implemented a software package: GFtbox. Using GFtbox one can start with a simple sheet of tissue (the canvas), lay out experimentally observed, or hypothesised, patterns of regulator activity and then grow the canvas in 3D. The final shape can be compared quantitatively with it's biological counterpart.

More details

<sgallery width="160" height="280" showarrows="false" showcarousel="false" showinfopane="false" timed="true" delay="4000"> LabelledCropped GPT Snapdragon 2010-000570-0003 double.png LabelledCropped GPT Snapdragon 2010-000570-0002 triple.png LabelledCropped GPT Snapdragon 2010-000570-0001-Wildtype.png </sgallery>

More details

Photos, Algorithms and Art

Tools and Demonstrations