AAMToolbox Details

What is AAMToolbox?

We wish to understand how patterns of gene activity in biological organs influence the developing shape. Our suggestion is that genes may regulate growth direction independently of growth rate. We formalised our ideas in the Growing Polarised Tissue Framework (reference 1, below). The icon is based on Fig. 4 of reference 1, and shows an asymmetrical spur that has grown under the influence of a polariser gradient, indicated by the arrows.